Alessandro Florenzi scored PSG's second on 77 minutes and Pablo Sarabia notched a fourth for the reigning champions as PSG climbed above Rennes on goal difference after a fifth successive win.
After Rennes defender Sacha Boey was sent off in the 35th minute for raising a foot near left back Reinildo's head, Lille took the lead five minutes later through forward Jonathan Bamba's low shot.
Kylian Mbappe capped a brilliant individual performance by scoring twice and creating another for Mauro Icardi as leaders Paris St Germain cruised to a comfortable 4-0 victory over Dijon in their Ligue 1 clash at the Parc des Princes
Champions League: PSG manager Thomas Tuchel defends change in team's system after defeat to Borussia Dortmund
PSG coach Thomas Tuchel defended a change in system against Borussia Dortmund despite a 2-1 loss in their Champions League Round of 16 first leg on Tuesday.
French Cup: Pablo Sarabia nets brace as Paris Saint-Germain complete thumping win over Dijon to seal semi-final spot
Paris Saint-Germain’s Pablo Sarabia scored twice as they swept past Dijon and into the semi-finals of the French Cup with a 6-1 thrashing on Wednesday.
Ligue 1: Marseille stay close to league leaders PSG with victory over Bordeaux; Stade Reims earn rare win Saint-Etienne
With its sixth consecutive league win, nine-time champion Marseille remained five points behind PSG, which has a game in hand.
Ligue 1: Reigning champions Paris Saint-Germain stunned by rock-bottom Dijon ahead of Club Brugge clash
Paris Saint-Germain suffered a shock 2-1 defeat at the hands of rock-bottom Dijon on Friday in a sapping setback to morale just days before they tackle Club Brugge in the Champions League.
Ligue 1: Marseille's sporadic run under Andre Villas-Boas continues with 1-1 draw at home against Rennes
The draw means Marseille are five points behind league leaders Paris Saint-Germain, who are two points ahead of Nantes and surprise package Angers
Ligue 1: Kylian Mbappe's 32nd goal helps PSG sign off season in style; Monaco ensure survival with win over Amiens
Monaco virtually made sure of their French Ligue 1 survival with a 2-0 win over Amiens on Saturday while champions PSG signed off their home campaign with Kylian Mbappe scoring his 32nd league goal of the season in a 4-0 win over Dijon.
Ligue 1: Amiens captain Prince Gouano halts match against Dijon to confront fans after alleged racial abuse
Friday's French Ligue 1 game between Dijon and Amiens was temporarily suspended after the visitors' captain Prince Gouano complained he was racially abused.
Ligue 1: Lyon's loss to struggling Dijon piles pressure on manager Bruno Genesio; AS Monaco inch towards safety
Lyon slipped to a second damaging defeat this week as a 3-1 loss to struggling Dijon and a hostile atmosphere at the Groupama Stadium piled the pressure on Bruno Genesio on Saturday.
Ligue 1: Nabil Kekir's winner helps Lyon warm up for Barcelona clash with victory over rock-bottom Guingamp
Lyon edged rock-bottom Guingamp 2-1 in Ligue 1 on Friday with a fabulous winner from captain Nabil Fekir, just days ahead of Barcelona's visit for a Champions League clash.
French Cup: Paris Saint-Germain score thrice in extra time to beat Villefranche in last-16 tie; Rennes defeat 10-man Lille
Paris Saint-Germain required extra time to overcome third-tier Villefranche in the last 16 of the French Cup while Rennes came from behind to beat 10-man Lille.
Ligue 1: Paris Saint-Germain face Lyon test after failing to reinforce depleted squad; Monaco look to get comeback underway
PSG remained light with contract rebel Adrien Rabiot frozen out, and Neymar ruled out due to a metatarsal injury that could see him miss up to 10 months of action
Ligue 1: Monaco succumb to defeat against Dijon just 24 hours after reappointing former boss Leonardo Jardim
Monaco suffered another damaging defeat as they lost 2-0 at Dijon in Ligue 1 on Saturday, just 24 hours after reappointing former boss Leonardo Jardim to take over from the sacked Thierry Henry.
Ligue 1: Dijon appoint former PSG boss Antoine Kombouare as head coach following dismissal of Olivier Dall'Oglio
After getting off to a flying start this season with three straight victories, Dijon have won just once since —against bottom club Guingamp — and languish third from bottom in Ligue 1.
Neymar Jr to miss Paris Saint-Germain's French League Cup tie against second-division Orleans with groin injury
The Brazil forward Neymar underwent tests at hospital on Monday and "is not at 100 percent" according to Tuchel, who said the results were otherwise reassuring.
Ligue 1: French league postpones five more games following ongoing protests and threat of more terror attacks
Half of the French Ligue 1 matches have been postponed for the second consecutive week because of heavy demand for police and security personnel amid ongoing protests and the threat of more terror attacks.
Ligue 1: Radamel Falcao scores twice against Amiens to lift Monaco out of relegation zone; Nice held by Angers at home
Radamel Falcao scored a pair of penalties as Thierry Henry's Monaco won 2-0 at fellow strugglers Amiens to climb out of the bottom three in Ligue 1 on Tuesday.
Ligue 1: Newly appointed AS Monaco coach Thierry Henry 'worried' after failing to win in four straight games
AS Monaco coach Thierry Henry is worried by his side's lack of victories since he's taken over but has insisted that the club can turn things around by working hard.