Karim Benzema, the heart of Madrid’s title run last season, set up Federico Valverde for the 14th-minute opener, and pressured Emerson into scoring an own goal
De Bruyne scored City's first from the penalty spot before having a hand in Phil Foden and Gabriel Jesus's goals.
Silva joined La Real on a free transfer earlier this month but returned a positive Covid-19 test after arriving to San Sebastian
Silva won 11 domestic trophies in his time in Manchester and is widely regarded as one of the Premier League's finest imports.
A training field will also be dedicated to Silva at City's practice facility.
Silva made 93 assists after his debut in the Premier League in August 2010, 29 more than any other player in that 10-year period.
Silva has a final shot at the one major trophy missing from his impressive collection, which includes winners' medals with Spain from the World Cup and two European championships.
Premier League: David Silva says trophy-laden career with Manchester City exceeded his wildest dreams
Silva has won 11 trophies in 10 seasons with Manchester City, including four Premier League titles, since arriving from Valencia in 2010.
De Bruyne, who has recorded 11 goals and 19 assists in the league this season, finished runner-up to Liverpool’s title winning captain Jordan Henderson in the annual FWA vote.
Premier League: Manchester City have Phil Foden so no need to replace David Silva, says Pep Guardiola
The talent of Manchester City’s 20-year-old midfielder Phil Foden, who scored twice in Monday’s 5-0 home win over Burnley, means the club do not have to invest in a replacement for the departing David Silva, says manager Pep Guardiola.
Premier League: Manchester City midfielder David Silva to stay with club till end of season, confirms Pep Guardiola
David Silva will stay at Manchester City until the end of the Premier League season, manager Pep Guardiola announced on Tuesday.
Premier League: From Vincent Kompany's undeniable presence to Eden Hazard's sublime skill, a look at Firstpost's 'Team of Decade'
After ten years of non-stop action and some truly excellent football, let's take a look at players that made this decade special in our Premier League Team of the Decade
Manchester City manager Pep Guardiola has denied reports that his contract contains a ‘break clause’ that could allow him to leave at the end of the season
Manchester City manager Pep Guardiola does not plan to bring in any players during the January transfer window but says the club must refresh the squad at the end of the season.
Premier League: Manchester City captain David Silva to miss Liverpool clash due to injury, confirms boss Pep Guardiola
Guardiola also ruled out taking Atalanta for granted and putting out a second-string Manchester City side for the game at the San Siro
Premier League: Injury concern for Manchester City; David Silva may miss key clash against league leaders Liverpool
'David Silva was injured. Five minutes before the first half ended he told me he had a muscular problem,' Guardiola told reporters.
League Cup: Manchester City midfielder Phil Foden says he wants to follow Raheem Sterling's example after making first start of season against Preston
Foden, the England under-21 international has seen his path blocked by an array of midfielders like David Silva, Kevin de Bruyne and Ilkay Gundogan
Premier League: Ruthless Manchester City put eight past Watford; VAR controversy continues as Leicester beat Tottenham
Although City fell one goal short of equalling the biggest Premier League margin of victory their swaggering display was the perfect way to erase the bitter taste from last weekend's shock defeat
Premier League: Manchester City to build statue outside Etihad stadium in honour of former captain Vincent Kompany
Vincent Kompany will miss playing in his Manchester City testimonial on Wednesday due to a hamstring injury, but was in attendance as the club also named a road at their training base after the centre-back.
Premier League: Sergio Aguero brace powers Manchester City to win; Tottenham suffer shock defeat to Newcastle
Pep Guardiola's City team did just that thanks to Aguero as City's record goalscorer hit another milestone with a clinical double in the south-coast sunshine