Iniesta helped Kobe, currently fifth in the 20-team J-League, reach the semi-finals of last year's Asian Champions League.
AFC Champions League 2021: Tajikistan's Istiqlol hand Al Hilal thrashing in shock win; Shabab Al Ahli beat AGMK
Three-times continental champs Al Hilal had beaten Istiqlol 3-1 on Wednesday but were in for a massive shock in the return.
For FC Goa, this was the second such result in as many matches. The Goan side had also played out a goal-less draw against Qatar's Al Rayyan in their first Group E match on Wednesday.
Defending CSL champions Jiangsu FC withdraw from Asian Champions League following financial collapse
Jiangsu won the Chinese Super League for the first time in November, but ceased operations last month after their struggling owners pulled the plug.
Shanghai, who initially missed out on the AFC tournament after finishing fourth in last year's domestic championship, have now been given a berth in the play-offs in April.
Asia's premier club tournament kicks off in mid-April, with group stage matches taking place in one West Asian and one East Asian hub.
Asian Champions League: Junior Negrao double powers Ulsan Hyundai Motors to second continental trophy
The South Korean giants also achieved the feat in record fashion, winning their ninth consecutive match in the tournament to equal their winning streak of 2012 when they won the title for the first time.
Asian Champions League: Junior Negrao's extra-time winner sees Ulsan Hyundai Motors book final berth
Hotaru Yamaguchi’s 52nd-minute goal for Vissel Kobe was cancelled out by Yoon Bit-garam’s 81st-minute strike before the match went into extra-time at the Al Sadd Sports Club.
Asian Champions League: Suwon Samsung Bluewings grab last round-of-16 spot with two-goal win over Vissel Kobe
The South Koreans needed to win by a two-goal margin to overtake China’s Guangzhou Evergrande on goal difference and that was exactly what they did as Kim Gun-hee and Lim Sang-Hyeob each struck in the second half at the Khalifa International Stadium in Doha.
Coronavirus-struck defending champions Al Hilal kicked out of Asian Champions League with depleted squad
Al Hilal were "deemed to have withdrawn from the competition" after failing to name the required 13 players for their AFC Champions League (West) Group B match in Doha.
The 32 teams from top leagues in Asia started the continental competition in February, but the tournament was suspended the following month because of the COVID-19 pandemic.
AFC Champions League: Andres Iniesta sets up three goals in Vissel Kobe's victory over Johor Darul Tazim
Andres Iniesta set up three goals, all scored by Keijiro Ogawa, to lead Vissel Kobe to a 5-1 win over Malaysian champions Johor Darul Tazim on Wednesday in the Asian Champions League.
Iran football clubs reach compromise with AFC over relocation of Asian Champions League matches to UAE
The Asian Football Confederation said it hosted club officials from Iran on Thursday and agreed how to stage three rounds of group-stage games in February and March
Asian Champions League: Salem Al-Dawsari, Bafetimbi Gomis score as Al Hilal beat Urawa Reds in lop-sided final
Salem Al-Dawsari and Bafetimbi Gomis scored in the second half on Sunday as Saudi Arabia’s Al Hilal beat Urawa Reds 2-0 to win the Asian Champions League final 3-0 on aggregate.
Barcelona said they paid 1.1 million euros ($1.25 million) for Hiroki Abe and assigned him to their reserve team, which plays in the third-tier Spanish Segunda B.
World Cup winning manager Luiz Felipe Scolari to clash with history-making female coach Chan Yuen-ting
World Cup winning coach Luiz Felipe Scolari, coach of Guangzhou Evergrande will take on female coach Chan Yuen-ting in the Asian Champions League.
Mohun Bagan's chances of making the Asian Champions League main round went up in smoke after the national football league champions were drubbed 0-6 by top Chinese side Shandong Luneng FC in the second round qualification match in Jinan on Tuesday.