Niko Kovac's Monaco have hauled themselves back into contention following a run of 13 wins in 16 matches since the start of the calendar year.
Germany lined up before the Iceland game in black T-shirts with white lettering to spell out "Human Rights", while Norway donned T-shirts with the message "Human rights, on and off the pitch" before their qualifier against Gibraltar.
Lyon were in cruise control with a 3-0 lead courtesy of goals from Lucas Paqueta in the ninth minute, Houssem Aouar after 28 minutes and a penalty from Memphis Depay just before the half-time break.
Lyon have lost just one of their last 21 Ligue 1 matches as they bid for a first league title since the most recent of their seven straight crowns in 2008.
PSG are second at the season's halfway stage, a point behind the leaders Lyon and ahead on goal difference of third-placed Lille, who triumphed 1-0 at Nimes.
Forward Karl Toko Ekambi put the home side ahead in the 21st minute when he volleyed in Memphis Depay's brilliant cross from the left. Reims midfielder Moreto Cassama was sent off 10 minutes later for fouling Depay as he was running through on goal.
Ligue 1: Lille play out 1-1 draw with 10-man Lyon to remain unbeaten, trail leaders PSG by two points
Jonathan Bamba put Lille ahead in the 21st minute with a fine strike, but Lyon equalized in the 40th when Lille defender Zeki Celik diverted an effort from Houssem Aouar into his own net.
Ligue 1: Lille register big win over Lens to move to top of league table; Lyon beat struggling Strasbourg
Lille are top of the French league, undefeated and with the fewest goals conceded, after beating northern rival Lens 4-0 on Sunday to move two points above defending champion Paris Saint-Germain.
Ligue 1: Lyon's frustrating start to new season continues with uninspiring goalless draw against Nimes
Memphis Depay, who has been linked with a move to Barcelona, and Moussa Dembele were both in the Lyon starting line-up but neither figured strongly in a lacklustre performance.
Memphis Depay scored what might be his farewell goal for Lyon on Tuesday in a 2-1 Ligue 1 defeat at Montpellier which could be his final match before a rumoured move to Barcelona.
New Barcelona boss Ronald Koeman has been on the hunt for a striker after telling Uruguayan Luis Suarez he wasn't in his plans for the coming season.
Lyon had eliminated Juventus and progressed to the quarterfinals on away goals after a 2-2 draw on aggregate.
Champions League: ‘Very, very small’ hope of Kylian Mbappe playing in Atalanta clash, says PSG coach Thomas Tuchel
Tuchel was asked at a news conference on Thursday ahead of Friday's League Cup final against Lyon if he has any hope that Mbappé can play against Atalanta in Lisbon.
Ligue 1: Netherlands international Memphis Depay returns to training with Lyon six months after suffering knee injury
The 26-year-old Depay, previously at PSV Eindhoven and Manchester United, tore the anterior cruciate ligament in his left knee in a Ligue 1 clash against Stade Rennes on 15 December.
French League Cup: Lyon win penalty shootout after 2-2 draw against Lille to register place in final
'We could have done without Lille's equalizer, but a shootout was nice for our supporters,' said Lyon coach Rudi Garcia.
Dembélé's firm drive in the 53rd minute came after he was set up by Cornet, who equalized three minutes earlier for Lyon
Kylian Mbappe scored twice as Paris Saint-Germain moved seven points clear at the top of the French league with a resounding 4-0 win at 10-man Saint-Etienne on Sunday.
Juventus centre-back De Ligt missed Wednesday's Champions League win at Lokomotiv Moscow with an ankle injury, while Depay will sit out Lyon's Ligue 1 game against rivals Marseille this weekend with a thigh problem
Euro 2020 Qualifiers: Belgium book place in next year's event after thrashing San Marino; Netherlands beat Northern Ireland
Belgium became the first team to qualify for the 2020 European Championship finals as Romelu Lukaku scored twice in a 9-0 thrashing of San Marino in Brussels on Thursday, while the Netherlands needed a late comeback to beat Northern Ireland.
Euro 2020 qualifiers: Belgium, Netherlands hit four goals to clinch victories; Germany secure crucial win over Northern Ireland
Belgium and the Netherlands both cruised to 4-0 wins over Scotland and Estonia respectively in Euro 2020 qualifying on Monday, while Germany claimed a crucial victory over Northern Ireland in their bid to qualify for next year's finals.