PSG coach Mauricio Pochettino missed the match after testing positive for COVID-19 before the game.
Ligue 1: Lille suffer first defeat of season at Brest, Lyon grab derby bragging rights over St Etienne
Paris Saint-Germain pulled five points clear at the top of the French league after Lille lost 3-2 at Brest on Sunday and surrendered the only remaining unbeaten record.
Rennes could have moved to the top of Ligue 1 with a victory, instead, they suffered their first defeat of the season as, for the fourth time in four games, they blew a lead. This time they did not even gain a draw.
PSG move up to second in the early table, a point behind leaders Rennes who play Reims on Sunday.
Marseille began their campaign with a 3-2 win at Brest as winger Florian Thauvin starred.
Marseille, who had to cancel what would have been the Ligue 1 season opener last Friday because of the five existing coronavirus cases, added that they had notified the French league about the new infections.
After Rennes defender Sacha Boey was sent off in the 35th minute for raising a foot near left back Reinildo's head, Lille took the lead five minutes later through forward Jonathan Bamba's low shot.
Marseille missed the creativity of Dimitri Payet as it dropped points in the race for a Champions League place after being held 0-0 at home by Angers
Ligue 1: Mauro Icardi nets first league goal as PSG thump Angers; Montpellier beats Monaco to climb to sixth place
Sarabia scored one goal and set up two more with Neymar completing the rout late as PSG kept a two-point lead over Nantes, which beat Nice 1-0 with an 86th-minute goal by Moses Simon. Angers is in third place, five points behind PSG.
Ligue 1: Memphis Depay helps Lyon snap winless streak with victory over Angers, maintain push for Champions League spots
Memphis Depay helped Lyon defeat Angers 2-1 in Ligue 1 on Friday to end a three match winless run and maintain their push for Champions League football next season.
Ligue 1: Paris Saint-Germain face Lyon test after failing to reinforce depleted squad; Monaco look to get comeback underway
PSG remained light with contract rebel Adrien Rabiot frozen out, and Neymar ruled out due to a metatarsal injury that could see him miss up to 10 months of action
Ligue 1: Memphis Depay scores brace to help Lyon beat Guingamp; Angers end Montpellier's winning streak
An inspired Memphis Depay scored twice and grabbed two assists as Lyon recovered from falling behind to last-placed Guingamp to win 4-2 in Ligue 1 on Saturday.
Ligue 1: Jonathan Bamba scores twice against former club to guide Lille past Saint-Etienne; Strasbourg held by Angers
In-form Lille youngster Jonathan Bamba scored twice against former club Saint-Etienne to fire Christophe Galtier's men to a 3-1 win which cut Paris Saint-Germain's lead in Ligue 1 on Saturday.
Ligue 1: Thiago Motta sent off, but Kylian Mbappe's double guides leaders Paris Saint-Germain past Angers
Kylian Mbappe grabbed both goals as runaway leaders Paris Saint-Germain defeated Angers 2-1 in Ligue 1 on Wednesday despite losing veteran midfielder Thiago Motta to an early red card.
Ligue 1: Neymar's solitary goal helps Paris Saint-Germain edge past Toulouse; AS Monaco thrash Angers 4-0
PSG stretched their advantage at the top to 12 points courtesy of Neymar's 19th Ligue 1 goal of the season, while Monaco thrashed Angers 4-0 to go second.
Ligue 1: French Football Federation suspends referee over kicking row during clash between PSG and Nantes
Referee Tony Chapron kicked Diego Carlos of Nantes towards the end of Sunday's match against Paris Saint-Germain after being knocked over when the pair collided in a bizarre incident.
Nantes head coach Claudio Ranieri admitted he "deserved" to be sent to the stands after his dismissal during Sunday's 1-0 win over Angers for putting his hands on the fourth official.
Ligue 1: Edinson Cavani scores 100th league goal as Paris Saint-Germain thrash Angers; Monaco defeat Guingamp 6-0
A second successive five-goal victory for PSG means they remain unbeaten in all competitions this season, while Angers are still without a home win.
Neymar will miss Paris Saint-Germain's trip to Angers on Saturday with a slight injury, while Angel Di Maria and Marquinhos will stay home as their wives are expecting children.
Ocampos bagged his first soon before the half hour mark, prodding in from close range after Nice's defence failed to deal with a cross