Vertonghen briefly tried to play on after an aerial collision involving teammate Toby Alderweireld and Ajax goalkeeper Andre Onana, but he soon had to be helped from the field and was seen vomiting on the pitch.
Premier League: Tottenham defender Toby Alderweireld sidelined for up to four weeks by adductor injury
Alderweireld sustained an adductor injury in Saturday's win against Manchester City.
Premier League: Leicester's top four hopes under threat after loss to Bournemouth; Tottenham win north London derby
A 4-1 capitulation at relegation-threatened Bournemouth on Sunday summed up Leicester's form since the Premier League returned from its three-month coronavirus-enforced shutdown.
Coronavirus Outbreak: From Roger Federer to Kevin Pietersen, a look at how the sporting world is coping with self-isolation
We at Firstpost take a look at what sportspersons around the world have been getting up to in self-isolation this week
Premier League: Tottenham Hotspur's Belgian defender Toby Alderweireld signs fresh contract with club until 2023
Belgian defender Toby Alderweireld has signed a new contract with Tottenham Hotspur until 2023, the Premier League club said on Friday.
Premier League: Players still committed to Tottenham cause says manager Mauricio Pochettino after Bayern defeat
Pochettino, in his sixth season at the club, pointed out that the Bayern disaster came just three days after last season's Champions League finalists had battled to beat Southampton with 10 men
League Cup: Mauricio Pochettino admits Tottenham squad is 'unsettled' after shock defeat to fourth-tier Colchester
Pochettino's Tottenham were beaten 4-3 on penalties against Colchester after being held to a goalless draw by a club 71 places below them, with Christian Eriksen and Lucas Moura both missing during the shoot-out.
Premier League: Arsenal look to gain upper hand, buck the trend against depleted rivals Tottenham Spurs
The balance of power between the rivals has swung the Spurs' way over the past three seasons as they have become north London's Champions League regulars
Champions League: Mauricio Pochettino's Tottenham suffered stage fright against Liverpool, but it's not end of road for club
Nerves may have blunted their patterns of play but Spurs did not lose to Liverpool because there was a considerable gap in quality.
Champions League: Mauricio Pochettino will bank on Tottenham's 'animal spirit' to upset title favourites Liverpool in final
At different points during Pochettino’s tenure, Tottenham as animals has meant different things – energetic, swarming in groups, sensuous, driven to instinctual bursts of brilliance and self-destruction, grasping the graspable.
Champions League: Tottenham manager Mauricio Pochettino open to change in football's concussion protocols
Mauricio Pochettino said he was open to a change in football's concussion protocols as Tottenham wait for an update on the health of Jan Vertonghen.
Champions League: British charity calls for rolling substitutions in event of head injury after Jan Vertonghen incident
Tottenham manager Mauricio Pochettino told reporters the Tottenham medical staff followed the necessary protocols before allowing Vertonghen back onto the pitch
Champions League: New generation Ajax mirror Johan Cruyff's Total Football to unsettle Tottenham in first leg
Spurs can pat their backs for clinging on to the tie and making a comeback after a first half that saw Ajax remind the world why they are the masters of Johan Cruyff's Total Football.
Premier League: Mauricio Pochettino backs under-fire Tottenham captain Hugo Lloris despite costly error against Liverpool
Mauricio Pochettino said on Tuesday that Hugo Lloris will remain in goal for Tottenham despite a series of costly errors this season.
Premier League: Tottenham manager Mauricio Pochettino says 'heroic' players have finally found their place
Despite their recent run of bad results, Spurs under Pochettino have punched above their weight, without a single signing in the past 15 months.
Premier League: Liverpool beat Spurs via late Toby Alderweireld own-goal to rescue title chances from brink of collapse
Liverpool's hopes of ending a 29-year wait to win the title looked set to be dealt a massive blow as Lucas Moura's strike 20 minutes from time cancelled out Roberto Firmino's early opener
Premier League: Chelsea manager Maurizio Sarri says dropped Kepa Arrizabalaga still his first-choice goalkeeper
Maurizio Sarri believes Chelsea's crucial 2-0 win over Tottenham can save their season after his decision to drop Wembley rebel Kepa Arrizabalaga paid off on Wednesday.
Premier League: Tottenham Hotspur trigger extension clause in wantaway Belgian Toby Alderweireld's contract
Alderweireld, who attracted interest from Manchester United in the close season after he rejected a long-term deal, has been the rock at the heart of the defence this term.
Premier League: Tottenham Hotspur to extend Toby Alderweireld's contract by one year, says Mauricio Pochettino
The move prevents Toby Alderweireld, who has been linked with a move to Manchester United, from leaving on a free transfer at the end of the season.
Premier League: Tottenham boss Mauricio Pochettino says squad is being pushed to the limit after World Cup exertions
Mauricio Pochettino's team selection has come under intense scrutiny this season as he tries to perform a balancing act between resting his players and fielding a strong side.