Star striker Erling Braut Haaland is out until January with a leg injury, while midfielders Thomas Delaney, Raphael Guerreiro, Mahmoud Dahoud and Mateu Morey are all missing with various ailments.
Bundesliga: Borussia Dortmund rue missed chances after being held to first goalless draw of season against Hanover 96
For Dortmund, the result was in stark contrast to the storming 4-1 win over RB Leipzig on the opening weekend.
Axel Witsel scored with a stunning bicycle kick on his Dortmund home debut as his side roared back with a 4-1 win against RB Leipzig despite conceding after just 31 seconds.
International Champions Cup 2018: Mario Gotze penalty guides Borussia Dortmund past young Manchester City
Pep Guardiola’s start to his pre-season campaign ended in defeat as Borussia Dortmund captain Mario Gotze’s first-half penalty was enough to see off the Premier League champions Manchester City 1-0 at Soldier Field in Chicago.