Barcelona are now five points clear of rivals Real Madrid who suffered a shock 3-2 defeat at Rayo Vallecano.
The winners of the eight knockout round play-off ties will advance to the last 16, for which the eight Europa League group winners all qualified automatically.
Despite glorious years in his prime, making a case for being the club's best ever defender, winning three Champions Leagues, eight La Liga titles and seven Copas del Rey with Barca, recent seasons have seen Gerard Pique and the other veterans linked with repeated failures in Europe.
Gerard Pique bows out with three Champions League titles for his childhood club Barcelona and the 2010 World Cup and Euro 2012 with Spain.
Barcelona were eliminated in the group stage of the Champions League for the second consecutive season on Wednesday even before a 3-0 loss at home against Bayern Munich.
Champions League elimination certainly won't help Barcelona's financial situation, but a more worrying issue are the overblown salaries.
Big football clubs Barcelona, Real Madrid, and Athletic de Bilbao along with the Spanish Football Federation, are at crossroads against La Liga and other amateur clubs.
Champions League: Barcelona will fight hard against Bayern even if they're eliminated before kickoff, says Xavi
Barcelona could be eliminated even before their home meeting with Bayern Munich on Wednesday gets underway if Inter Milan beat Viktoria Plzen at home.
Robert Lewandowski, the top scorer in LaLiga, extended his domestic tally to 11 goals and his brace, along with Ansu Fati's strike ensured a win for Barcelona.
The trial is the culmination of a years-long legal saga over Neymar's 2013 move from Santos to Barcelona.
Karim Benzema and Federico Valverde scored first-half goals, and Rodrygo added another in second-half stoppage time as Real Madrid won the first “clásico” of the season to move three points ahead of Barcelona in the league standings.
Despite financial troubles, both Real Madrid and FC Barcelona have managed to field an expensively assembled squad for El Clasico.
Defeats on the road against Bayern Munich and Inter Milan, followed by a home draw against the Italian side have left Barca fans wondering if the summer shopping spree was worth it in the end.
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LaLiga leaders Barcelona take on Real Madrid in the season's first Clasico on Sunday at the Santiago Bernabeu stadium.
Gerard Pique played Nicolo Barella onside and let the ball travel through to him to level for Inter at 1-1, with Sergio Busquets softly ceding possession for the Italians' second goal at Camp Nou, scored by Lautaro Martinez
Champions League: 'We'll give everything', Xavi says Barcelona looking for revenge against Inter Milan
Barcelona lost 1-0 in Italy last week and only a win at Camp Nou will give them a realistic chance of qualifying for the knock-out phase and avoiding a second successive group stage elimination.
Inter Milan visit Camp Nou in a near life-or-death Champions League clash, before Barcelona visit the Santiago Bernabeu in a battle to move clear at the top of LaLiga.
Griezmann has been on loan at Atletico since August 2021 after a difficult spell at Camp Nou, following his €120 million (116.5 million dollar) move in 2019.
LaLiga: Barcelona latch on to Pedri's goal for a shaky win over Celta Vigo a week ahead of El Clasico
FC Barcelona somehow held on to Pedri's first-half goal in front of home fans at Camp Nou as Celta Vigo were at fault of missing plenty of chances during a dominant show against the 26-time champions.