Firstpost
  • Home
  • Video Shows
    Vantage Firstpost America Firstpost Africa First Sports
  • World
    US News
  • Explainers
  • News
    India Opinion Cricket Tech Entertainment Sports Health Photostories
  • Asia Cup 2025
Apple Incorporated Modi ji Justin Trudeau Trending

Sections

  • Home
  • Live TV
  • Videos
  • Shows
  • World
  • India
  • Explainers
  • Opinion
  • Sports
  • Cricket
  • Health
  • Tech/Auto
  • Entertainment
  • Web Stories
  • Business
  • Impact Shorts

Shows

  • Vantage
  • Firstpost America
  • Firstpost Africa
  • First Sports
  • Fast and Factual
  • Between The Lines
  • Flashback
  • Live TV

Events

  • Raisina Dialogue
  • Independence Day
  • Champions Trophy
  • Delhi Elections 2025
  • Budget 2025
  • US Elections 2024
  • Firstpost Defence Summit
Trending:
  • Nepal protests
  • Nepal Protests Live
  • Vice-presidential elections
  • iPhone 17
  • IND vs PAK cricket
  • Israel-Hamas war
fp-logo
Scientists derive a way to synthesise nano-particles using eggshells for drug delivery
Whatsapp Facebook Twitter
Whatsapp Facebook Twitter
Apple Incorporated Modi ji Justin Trudeau Trending

Sections

  • Home
  • Live TV
  • Videos
  • Shows
  • World
  • India
  • Explainers
  • Opinion
  • Sports
  • Cricket
  • Health
  • Tech/Auto
  • Entertainment
  • Web Stories
  • Business
  • Impact Shorts

Shows

  • Vantage
  • Firstpost America
  • Firstpost Africa
  • First Sports
  • Fast and Factual
  • Between The Lines
  • Flashback
  • Live TV

Events

  • Raisina Dialogue
  • Independence Day
  • Champions Trophy
  • Delhi Elections 2025
  • Budget 2025
  • US Elections 2024
  • Firstpost Defence Summit
  • Home
  • Tech
  • News & Analysis
  • Scientists derive a way to synthesise nano-particles using eggshells for drug delivery

Scientists derive a way to synthesise nano-particles using eggshells for drug delivery

Shikha T Malik • March 28, 2018, 21:28:42 IST
Whatsapp Facebook Twitter

New studies suggest that nanoparticles in eggshells have better physical and biological properties than synthetically derived ones.

Advertisement
Subscribe Join Us
Add as a preferred source on Google
Prefer
Firstpost
On
Google
Scientists derive a way to synthesise nano-particles using eggshells for drug delivery

Eggshells are among the most commonly discarded kitchen waste. Now scientists are putting eggshells to some novel use – drug delivery – by deriving nanoparticles out of them. [caption id=“attachment_4409811” align=“alignleft” width=“380”]Representational image. Representational image.[/caption] A team of scientists at the Indian Institute of Technology (IIT) Madras have developed a method to use eggshells for synthesising nano-particles. These nanoparticles could be potential candidates for local drug delivery as well as a material for bone grafts. Nanoparticles are extremely tiny particles which can be customized for various biomedical applications like diagnostics, drug delivery etc. Researchers feel eggshell-derived nanoparticles may be suitable for use in humans as they have tested biocompatibility of calcium phosphate cement made from eggshells as dental implants in preliminary studies in humans. However, eggshell-derived nanoparticles are yet to be tested in humans.

Egg shell

Using microwaves, scientists synthesized carbonated calcium deficient hydroxyapatite (ECCDHA) nanoparticles from egg waste. These nanoparticles are similar to human bone in mineral composition. In order to check drug delivery efficacy of these nanoparticles, researchers compared them with synthetic hydroxyapatite nanoparticles and found them to be more efficient. They are better in loading and releasing drugs in a sustained manner compared to the synthetic nanoparticles. A higher drug-loading capacity means lesser quantity of nanoparticle material is needed for drug delivery. The efficacy of these particles was analyzed using an antibiotic as a test drug. “Apart from their ability to deliver the antibiotic, eggshell derived apatite nanoparticles also showed higher amount of bovine serum albumin (BSA) protein delivery, which means they may be employed for delivering growth factors for bone regeneration”, Prof. Sampath Kumar, who led the team, told India Science Wire. In addition to drug delivery, the presence of ions like strontium, magnesium, fluoride and sodium in small amounts in these nanoparticles makes them potentially useful as graft materials for bone regeneration. “Since these eggshell derived particles are very similar to human bone with respect to their mineral composition, we propose that these may be potential candidates for bone substitutes and may be used for treatment of infections associated with bone loss,” said Kumar. Hydroxyapatite is a major mineral base of human bone and is one of the most studied biomaterials for more than half a century. However, synthetic hydroxyapatite drastically varies from biological apatite found in human bone. It lacks the trace elements, which are highly essential for bone growth and remodeling. “Hydroxyapatite with chemical composition similar to biological apatite would be beneficial for bone applications”, pointed out Dr M Ramalingam, co-author of the study. The research team has tested eggshell derived calcium phosphate cements in humans. “Preliminary clinical studies with six patients have indicated clinical efficacy of eggshell derived cements in treating bone (dental) defects, demonstrating complete resorption with new bone formation”, Kumar said. These studies suggest that the eggshell nanoparticles have better physical and biological properties than synthetically derived ones. The team included R. Jayasree, K. Madhumathi, Rakesh P. Nankar, Mukesh Doble, and T. S. Sampath Kumar at IIT Madras; Deepti Rana and Murugan Ramalingam from CMC Vellore. The study has been published in Journal of Nanoscience and Nanotechnology and was funded by the Department of Biotechnology (DBT). India Science Wire

Tags
NewsTracker Nanoparticles drug delivery
End of Article
Latest News
Find us on YouTube
Subscribe
End of Article

Top Stories

Israel targets top Hamas leaders in Doha; Qatar, Iran condemn strike as violation of sovereignty

Israel targets top Hamas leaders in Doha; Qatar, Iran condemn strike as violation of sovereignty

Nepal: Oli to continue until new PM is sworn in, nation on edge as all branches of govt torched

Nepal: Oli to continue until new PM is sworn in, nation on edge as all branches of govt torched

Who is CP Radhakrishnan, India's next vice-president?

Who is CP Radhakrishnan, India's next vice-president?

Israel informed US ahead of strikes on Hamas leaders in Doha, says White House

Israel informed US ahead of strikes on Hamas leaders in Doha, says White House

Israel targets top Hamas leaders in Doha; Qatar, Iran condemn strike as violation of sovereignty

Israel targets top Hamas leaders in Doha; Qatar, Iran condemn strike as violation of sovereignty

Nepal: Oli to continue until new PM is sworn in, nation on edge as all branches of govt torched

Nepal: Oli to continue until new PM is sworn in, nation on edge as all branches of govt torched

Who is CP Radhakrishnan, India's next vice-president?

Who is CP Radhakrishnan, India's next vice-president?

Israel informed US ahead of strikes on Hamas leaders in Doha, says White House

Israel informed US ahead of strikes on Hamas leaders in Doha, says White House

Top Shows

Vantage Firstpost America Firstpost Africa First Sports
Latest News About Firstpost
Most Searched Categories
  • Web Stories
  • World
  • India
  • Explainers
  • Opinion
  • Sports
  • Cricket
  • Tech/Auto
  • Entertainment
  • IPL 2025
NETWORK18 SITES
  • News18
  • Money Control
  • CNBC TV18
  • Forbes India
  • Advertise with us
  • Sitemap
Firstpost Logo

is on YouTube

Subscribe Now

Copyright @ 2024. Firstpost - All Rights Reserved

About Us Contact Us Privacy Policy Cookie Policy Terms Of Use
Home Video Shorts Live TV