The reigning world champion Indian ace had no answer to the in-form world number six Korean, who dictated terms from the word go.
BWF World Tour Finals: Sindhu beats Yamaguchi in thriller to enter final; Axelsen knocks Sen out in semis
It will be Sindhu's third final appearance in the season-ending tournament. She had won the title in 2018 to become the only Indian to achieve the feat.
BWF World Tour Finals: Already qualified for semis, PV Sindhu loses final group match, Srikanth bows out
Sindhu, a two-time Olympic medallist, couldn't apply enough pressure on the world No 10 Chochuwong to go down fighting 12-21 21-19 14-21 in a match that lasted an hour and 11 minutes.
The reigning Olympic champion outplayed the unseeded Sen 21-15, 21-14 in the season-ending tournament held on the holiday island of Bali
World number 14 Srikanth, who had reached the knockout stage in the 2014 edition of the year-ending event, went down 18-21 7-21 to three-time junior world champion Vitidsarn in a 46-minute men's singles match.
BWF World Championships: PV Sindhu gets first round bye in tournament draw, likely to face Tai Tzu Ying in quarters
Sindhu, who won a bronze in the Tokyo Olympics, has been seeded sixth in the 12-19 December showpiece event.
It will be the best ever representation for India at the year-end tournament with as many as seven of them qualifying for the $1,50,000 event.
Third seed Sindhu, a two-time Olympic medallist, lost 21-15 9-21 14-21 to world number eight and second seeded Ratchanok in 54 minutes for her third semifinal finish on the trot
Third seed Sindhu, the reigning world champion, had to toil hard to get the better of Yujin 14-21, 21-19, 21-14 in the quarter-final that lasted an hour and six minutes.
Up against Li for the first time, world No.7 Sindhu looked completely in control from the beginning
After a slow start, Sindhu, the reigning world champion, engineered a turnaround to register a hard-fought 17-21, 21-17, 21-17 win over Japan's Ohori in one hour 10 minutes to advance to the pre-quarterfinals.
Sindhu, who is one of the nine candidates nominated for the six positions, will be contesting the election during the World Championships in Spain on 17 December
Just days after their semifinal finishes at Indonesia Masters Super 750, the two top Indian shuttlers will begin their campaign at the World Tour Super 1000 event in their quest for title
Indonesia Masters 2021: PV Sindhu, Kidambi Srikanth exit after defeat in semis as Indian campaign ends
Sindhu, who had a superior 12-7 head-to-head record against the Japanese shuttler going into Friday's tie, was no match to her rival, losing 13-21 9-21 in a one-sided duel that lasted just 32 minutes
With the win the two-time Olympic medallist Sindhu extended her dominating head-to-head record against the Turkish shuttler to 4-0
Reigning world champion Sindhu, seeded third, record a 21-15 21-19 win over Thailand's Supanida Katethong in a 43-minute women's singles match to set up a second-round clash with Spain's Clara Azurmendi
The 2019 World Championship in Switzerland was Sindhu's last title.
PV Sindhu continued her impressive run at the French Open badminton tournament by sailing into the women's singles semi-finals with a straight-game win over Thailand's Busanan Ongbamrungphan
India's Sourabh Verma, however, bowed out of the competition after losing 12-21 9-21 to Japan's Kenta Nishimoto in the second round.