Europa League: Arsenal wait on Pierre-Emerick Aubameyang and Martin Odegaard ahead of Slavia Prague tie
Aubameyang and Odegaard, who is on loan from Real Madrid, missed training Tuesday because of illness and an ankle injury respectively.
Club captain Aubameyang signed a lucrative new three-year contract last year but has struggled for form this season and was dropped for last month's north London derby after arriving late.
Lacazette's contract is up next year and several clubs including Serie A side Roma and Spanish team Atletico Madrid have been linked with moves for him.
Arsenal's realistic hopes of Champions League football next season now hinge on success in the Europa League as they are nine points adrift of the top four down in ninth.
Europa League: Mikel Arteta holds 'positive' talks with Pierre-Emerick Aubameyang after dropping striker
Aubameyang was left on the bench after reportedly arriving late for a team meeting before Arsenal beat north London rivals Tottenham 2-1 on Sunday.
Premier League: Arteta 'moving forward' after dropping Pierre-Emerick Aubameyang for discipline breach
Arteta said the issue was subject to an internal process without divulging further details on what the Gabon international had done.
Premier League: Leicester move to second after win over Brighton; Arsenal's top-four hopes fade after loss at Burnley
Depleted by a series of injuries to key players, Leicester have looked fatigued in recent weeks and fell behind after 10 minutes when Adam Lallana swept home his first Brighton goal.
Steven Gerrard's Rangers progressed following their 5-2 win over Belgian side Antwerp at Ibrox, with five different players on target for the Scottish league leaders.
Tattoo artist Alejandro Nicolas Bernal posted the social media clip on 9 February where Aubameyang is seen to get a new tattoo on his hand.
Premier League: Pierre-Emerick doubtful for Arsenal-Manchester United showdown due to mother's health issues
The club captain was absent for the FA Cup defeat at Southampton on Saturday as well as the 3-1 Premier League victory against the same opposition three days later.
Newcastle do remain firmly in a relegation fight after a ninth consecutive game without a win despite Steve Bruce making eight changes.
FA Cup: Defending champions Arsenal beat Newcastle in extra time; non-league Chorley shock virus-hit Derby County
Leicester rested Jamie Vardy and James Maddison at second-tier Stoke but still won 4-0 as James Justin, Marc Albrighton, Ayoze Perez and Harvey Barnes all netted.
Premier League: Arsenal skipper Pierre-Emerick Aubameyang urges young players to be patient for first-team chances
The form of other experienced players like Granit Xhaka and Willian has fallen away leading to calls for young players to be selected by coach Mikel Arteta.
Arsenal have suffered their worst start to a season since the 1974/75 campaign, with just 14 points from as many games, and they are seven points worse off than when they sacked Unai Emery last year
Premier League: Arsenal players must take responsibility for Arsenal's 'terrible' form, says Kieran Tierney
Burnley recorded their first-ever win at the Emirates on Sunday as a Pierre-Emerick Aubameyang own goal secured a 1-0 victory for the visitors after Granit Xhaka was sent off for the hosts.
Gabon skipper Pierre-Emerick Aubameyang was sanctioned for posting photos of his teammates who were forced to sleep on the floor while Gabon federation were fined $10,000.
The first north London derby of the season arrives on Sunday with Tottenham and Arsenal in vastly different situations.
Premier League: Liverpool set new Anfield record with win over Leicester; 10-man Arsenal hold Leeds United
Liverpool have now set a new club record of 64 unbeaten league games at Anfield.
Arsenal boss Mikel Arteta did not reveal if Willian will be dropped for Sunday's Premier League trip to Leeds.
The Gabon squad, including Arsenal star Pierre-Emerick Aubameyang, were forced to sleep on the floor at a Gambian airport before an Africa Cup of Nations qualifier recently.