Marcos Andre put Valladolid ahead in the 57th minute and Jose Campana equalised for the visitors by converting an 83rd-minute penalty kick.
Silva opened the scoring with a header on Sunday as Real Sociedad beat Celta Vigo 4-1 to take a one-point lead at the top of the league.
LaLiga: Valencia register big win in derby against Levante; Real Betis beat Alaves to make winning start
It was a thrilling return to LaLiga for Manuel Pellegrini as Real Betis won 1-0 against Alaves.
The come-from-behind victory in Bilbao left Sevilla tied on points with third-place Atlético Madrid and increased its gap to fifth-place Villarreal to six points with three rounds to go. Only the top four qualify for next season's Champions League.
LaLiga: Sevilla's Lucas Ocampos scores then makes winning save against Eibar; Real Sociedad held by Levante
Ocampos scored in the 56th minute, then had to put on the goalkeeper's gloves and jersey after Tomás Vaclik hurt his left leg while colliding with an opponent in the final minute of stoppage time.
LaLiga: Villarreal move closer to Champions League spot after win against Real Betis; Valencia suffer third straight loss
Villarreal's Gerard Moreno converted a seventh-minute penalty kick and added to the lead from inside the area in the 30th to become the league's top-scoring Spaniard with 15 goals
LaLiga: Karim Benzema's clever assist helps Real Madrid beat Espanyol and go clear at top; Villarreal score win over Valencia
Real Madrid and Barcelona have six games left with Madrid leading by two points. Madrid holds the tiebreaker on head-to-head results in the event they finish level on points.
LaLiga: Barcelona beat Athletic Bilbao to move back on top; Atletico Madrid secure win against Levante
Barcelona earned a hard-fought 1-0 win against Athletic Bilbao on Tuesday to put the pressure back on Real Madrid in the Spanish league.
LaLiga: Diego Simeone’s Atletico Madrid earn hard-fought victory over Valladolid; Getafe held by Eibar
Atlético Madrid honoured the club’s victims of the coronavirus pandemic and earned a hard-fought victory Saturday in their first home game since the Spanish league resumed.
Third-placed Sevilla were on their way to opening a six-point gap to fourth-placed Real Sociedad had it held on to the victory.
LaLiga: Gonzalo Melero converts last-minute VAR-awarded penalty to help Levante hold Valencia to 1-1 draw
Gonzalo Melero converted the last-gasp spot kick to cancel out Rodrigo’s late opener as Europe-chasing Valencia stayed seventh on 43 points from 28 games.
Levante coach Paco Lopez has said he hoped La Liga did not allow supporters to attend matches in the final stretch of the season because his side were playing home games at a different ground after assuming the fixtures would be played without spectators.
LaLiga: Espanyol the biggest name at stake in crowded relegation battle as Spanish league resumes this week
Espanyol were bottom of the standings on 20 points, six short of the safety zone, when the season was halted in March with 11 matches remaining.
LaLiga club logos explained: What does the tree on Athletic Bilbao's escudo mean? Is there an English reference to Barcelona's logo?
LaLiga: Barcelona should have taken advantage of 'worst' Real Madrid, says Gerard Pique after 0-2 defeat
Barcelona defender Gerard Pique rued his side’s failure to take a stranglehold on the Liga title race as they lost 2-0 at Real Madrid in Sunday’s ‘Clasico’ after dominating the first half and failing to take their early chances.
La Liga champions Barcelona fell to their first defeat in three games under new coach Quique Setien as they were beaten 2-0 away at Valencia
A late strike from Espanyol's Wu Lei stymied a superb performance by Luis Suarez to leave Barcelona tied on points atop LaLiga with Real Madrid at halfway stage of the season
LaLiga: Thrid-placed Sevilla drop points in title race as an own goal helps them secure 1-1 draw against Athletic Bilbao
Sevilla needed an own-goal to salvage a 1-1 draw at home against Athletic Bilbao on Friday as the Spanish league resumed after the winter break.
LaLiga: Barcelona stumble to draw against Real Sociedad; Atletico Madrid end winless streak with win over Osasuna
Barcelona were held to a 2-2 draw at Real Sociedad on Saturday, giving Madrid a chance to go into the midweek's clasico at Camp Nou Stadium with a two-point lead if they beat Valencia on Sunday.