Thomas Tuchel's unbeaten side sit top of the Premier League after winning four of their first five games, while Tottenham have suffered two successive top-flight defeats.
Premier League: Manchester United manager Ole Gunnar Solskjaer says team must 'do better' after midweek defeat
Aaron Wan-Bissaka was sent off against Young Boys in Tuesday's opening Group F encounter, with Jesse Lingard's errant back-pass gifting the Swiss hosts a goal in time added on in a 2-1 win.
Manager Gareth Southgate changed the entire starting XI following his side's comfortable 4-0 win in Hungary in midweek — the first time England had changed every player since 1982.
Leeds striker Patrick Bamford receives first England call-up, Gareth Southgate opts to rest Mason Greenwood
The Three Lions return to action against Hungary, Andorra and Poland for the first time since missing out on winning Euro 2020 on a penalty shootout to Italy in July.
Alexander-Arnold had to endure a nervous wait before learning he had made the cut after spending much of the season out of favour with Southgate.
Lingard said mental health deteriorated to the extent he contemplated quitting or at least taking a time-out from the game.
Premier League: Manchester United hit back to sink Tottenham Hotspur; Jesse Lingard lifts West Ham into 4th
Ole Gunnar Solskjaer's Manchester United trailed to Son Heung-min's first half strike, but United scored three times after the break through Fred, Edinson Cavani and Mason Greenwood.
The win allowed West Ham to dislodge Chelsea and move back into fourth place in the Premier League in pursuit of Champions League qualification for the first time.
Premier League: Jesse Lingard shines as West Ham move to fourth after win over Wolves; Crystal Palace hold Everton
Everton missed the chance to also move within three points of four, with a game in hand to come, as Michy Batshuayi's 86th minute equaliser salvaged a point for the Eagles at Goodison Park.
Arsenal's realistic hopes of Champions League football next season now hinge on success in the Europa League as they are nine points adrift of the top four down in ninth.
Lingard, who was a member of the England team that reached the World Cup semi-finals in 2018, last played for his country at the Nations League finals in June 2019.
Premier League: Kai Havertz shines as Chelsea secure victory over Everton; West Ham beat Leeds United
Chelsea are unbeaten in 11 games in all competitions – winning eight times – since Tuchel replaced the sacked Frank Lampard in January.
Algerian forward Benrahma has signed a contract until 2026 in a deal worth a reported £25 million ($34 million) plus £5 million in add-ons
Manchester United face the in-form Everton on Wednesday for a League Cup quarter-final clash.
Premier League: Manchester United boss Ole Gunnar Solskjaer wants Jesse Lingard to ease off on social media, return to form
Manchester United manager Ole Gunnar Solskjaer believes Jesse Lingard has toned down his social media activity in order to recapture his best form in the second half of the campaign.
Premier League: Manchester United's Jesse Lingard says club guilty of complacency against mid-table teams
Manchester United's inconsistent start to the season during which they have struggled against mid-table teams can be attributed to complacency, according to midfielder Jesse Lingard.
Greater Manchester Police said a 41-year-old man was arrested on suspicion of a racially aggravated public order offense and he remains in custody for questioning
Premier League: Manchester United players targeted with racist taunts by Manchester City fan during derby win
The game was marred by Manchester United players Fred and Jesse Lingard being targeted with racist abuse and objects.