The Suns were down one with 0.9 seconds left when Crowder lofted a high pass on an out-of-bounds play on the baseline. A soaring Ayton came down the lane and stuffed it through the net over LA's Ivica Zubac as the crowd roared in disbelief at Phoenix Suns Arena.
Anthony Davis missed half of the 72-game regular season because of a string of injuries. LeBron James, who missed more than 20 games this season with a high right ankle sprain.
Phoenix took full advantage of the injury absence of the Lakers' Anthony Davis to dominate the defending NBA champions from early in the first quarter before romping to a comfortable win.
It was the first playoff game for several Suns players, including Booker, Ayton and Mikal Bridges, but they didn't look like post-season rookies against LeBron James and the Lakers.
The Jazz improved to 48-18 on the season and the win - combined with the Atlanta Hawks' victory over the Phoenix Suns - allowed them to reclaim first place in the NBA and top spot in the Western Conference
The New York Knicks were on their longest winning streak since a 13-game run late in the 2012-13 season.
The Lakers entered the game missing their two best players, LeBron James and Anthony Davis, but they overcame that with energetic play, strong perimeter shooting and a lockdown defence.
NBA: LeBron James opts for Giannis Antetokounmpo, Kevin Durant takes Kyrie Irving as first picks for All-Star Game
This is the fourth year of the NBA's playing captain format for the All-Star Game. James is 3-0, beating teams captained by Curry in 2018 and Antetokounmpo in the last two seasons.
NBA: Tim Hardaway Jr, Luka Doncic star in Dallas Mavericks win; Washington Wizards beat Los Angeles Lakers
Dallas were playing for the first time in eight days after two postponements because of a wintry weather blast in Texas. Kristaps Porzingis didn’t play after showing up on the injury report the day of the game with back stiffness.
NBA: Jerami Grant helps Detroit Pistons beat Phoenix Suns; Milwaukee Bucks suffer first home loss against Utah Jazz
LeBron James had 28 points, seven rebounds and seven assists, and Los Angeles overcame the absence of two injured starters to beat Chicago.
James Harden took the floor for the Rockets practice after joining the team late amid reports he wants to be traded
Under the deal, Paul and Abdel Nader will head to the Suns in exchange for Kelly Oubre, Ricky Rubio, Ty Jerome and Jalen Lecque. Oklahoma City will also receive a 2022 first-round draft pick
NBA: Portland Trail Blazer's Damian Lillard named MVP of restart, Phoenix Suns' Monty Williams best coach
Damian Lillard said his explosive performance in the bubble was a continuation of his form early in a season that was then disrupted by injury and the coronavirus pandemic.
The NBA fined Green $50,000 on Sunday for violating the league’s anti-tampering rule with his comments about Booker, the Phoenix Suns’ star guard.
NBA: Jimmy Butler scores season-high 38 points as Heat thrash 76ers; Kristaps Porzingis powers Mavericks to victory
Goran Dragic scored 24 points for Miami, Duncan Robinson had 19 and All-Star Bam Adebayo finished with 18 points, 11 assists and eight rebounds for the Heat
NBA: Goran Dragic scores 29 points as Heat ease to victory over Trail Blazers; Clippers edge past Knicks
Dragic tied a career-best with seven 3-pointers. Derrick Jones Jr scored 19 points for the Heat, who got 14 from Kendrick Nunn and 12 points in 22 minutes from little-used James Johnson — who was called upon largely because Miami was without Jimmy Butler
NBA: Mitchell Robinson, Julius Randle power Knicks to win over Trail Blazers; West-leading Lakers ease past Suns
Portland’s Damian Lillard was held to 11 points on 5-for-20 shooting after scoring 30 or more in the previous three games
NBA Rundown Week 3: Phoenix Suns emerge as league's biggest surprise so far; LA Lakers are most hated franchise
Bits and bobs from the week gone by in the NBA
NBA: Devin Booker helps Suns end Sixers' unbeaten run; Golden State Warriors record first win at new home arena
Phoenix's Devin Booker scored 40 points to lead the Suns over visiting Philadelphia 114-109 on Monday, delivering the first loss of the season to the NBA's last unbeaten team.
Kelly Oubre had 27 points and 13 rebounds, and the Phoenix Suns rallied from a 10-point late deficit to complete a season sweep of the NBA-leading Milwaukee Bucks with a 114-105 win