Even the dreamiest of dreamers from Manchester United would recognise that it would be against the odds to come away from Merseyside with another positive result after the 1-1 draw in October.
Premier League: Stoppage-time VAR controversy grabs headlines in Sheffield United's narrow win over West Ham
Three points take Sheffield United to fifth place, while West Ham remain in trouble in 16th place, two points above the bottom three.
Premier League: David Moyes determined to revive West Ham United's fortunes, secure long-term future in second stint at London club
Moyes said he had been given a second chance on the back of what he had achieved last time around, when he had been disappointed not to be retained, and could not wait to get started
Premier League: West Ham United reappoint David Moyes as head coach in bid to avoid relegation scrap
West Ham United have reappointed David Moyes as head coach on an 18-month deal to replace the sacked Manuel Pellegrini and help them move away from the bottom half of the table, the struggling Premier League club said on Sunday.
Manuel Pellegrini was fired by West Ham on Saturday after 18 months in charge, paying the price for an alarming slump in the Premier League that has seen the team plunge from fourth place into a relegation battle.
Premier League: Everton deny offering contract to any candidate despite reports of Carlo Ancelotti taking over as manager
Everton said on Monday they had not yet offered any candidate a contract to become their new manager after British media reports that Carlo Ancelotti was set to take over the struggling team.
Premier League: I'd be on the roof if we win at Manchester United, says Everton's interim manager Duncan Ferguson
Everton interim boss Duncan Ferguson said supporters can expect even wilder celebrations from him if they can pull off a rare Premier League victory at Manchester United
Premier League: Pep Guardiola's Manchester City looks to make an example out of Manchester United's fall in status
If Manchester United are to win tonight, a lot will depend on Marcus Rashford’s ability to pull the City defence apart on counter-attacks.
Premier League: Unai Emery is second in long line of victims to toxic discourse fermented by Arsenal Fan TV
Arsenal Fan TV has exclusively become the mouthpiece for knee-jerk reactions of match-going fans who demand their penny’s worth with little or no consideration for objectivity
Premier League: Gary Neville leads calls for Ole Gunnar Solskjaer to rid Manchester United of 'weeds' after Everton loss
Seldom can a Manchester derby — they host title-chasing City on Wednesday — have been less eagerly anticipated by United fans.
Checkatrade Trophy: From EFL Championship relegation to Wembley final, Sunderland make steady return from brink of oblivion
In a vivid display of English football's ability to inspire devotion throughout the darkest days, over 40,000 Sunderland fans will make a pilgrimage to Wembley on Sunday to celebrate their troubled club's rebirth
Premier League: Firing out-of-favour manager Jose Mourinho cost Manchester United $25 million, according to financial results
The compensation for dismissing Mourinho and six members of his coaching staff was disclosed among "exceptional items" in the latest set of financial results published on Thursday by United that showed record revenue.
Premier League: Manchester United reach agreement with Shandong Luneng for transfer of Marouane Fellaini
Manchester United have reached an agreement with Chinese Super League side Shandong Luneng for the transfer of midfielder Marouane Fellaini, but the deal could drag on with the transfer market in China open until 28 February
EFL Championship: Stoke City pay Luton Town $1.3million in compensation to sign Nathan Jones as manager
Nathan Jones became the front runner when former Fulham handler Slavisa Jokanovic said he was not interested and it was thought unlikely David Moyes would wish to manage a second-tier team
'Not the most wonderful time of the year for some:' Twitter reacts as Manchester United and Jose Mourinho part ways
A compilation of Twitter reactions to Portuguese manager Jose Mourinho's departure from Premier League club Manchester United.
Premier League: Jose Mourinho has full backing of Manchester United and fans, says former manager David Moyes
Mourinho reportedly faced the sack regardless of the outcome of the match with Newcastle but is still in position after United roared back to win 3-2 after trailing 2-0.
Jose Mourinho's position as Manchester United manager is not under immediate threat, senior figures at the club have said, denying a report he was set to be sacked.
Premier League: Manchester United boss Jose Mourinho set to be sacked regardless of result against Newcastle, says report
Jose Mourinho's turbulent time as Manchester United manager could end with him being sacked as soon as this weekend, according to a British press report.
Manchester United's misfiring players need to take responsibility for a "horrendous" display against West Ham that leaves them languishing in 10th place in the Premier League, defender Luke Shaw said.
Premier League: West Ham manager Manuel Pellegrini believes Felipe Anderson will add 'new dimension' to team
Anderson was the Hammers' seventh pre-season signing and former Manchester City manager Pellegrini, who took charge of the east London club after they decided against renewing David Moyes' contract