Figueiredo (20-1) earned his record-tying seventh stoppage victory in the 125-pound division by clamping onto Perez's neck out of a scramble at 1:57 in the opening round.
Khabib Nurmagomedov (28-0) holds the longest active unbeaten streak in MMA, and he became the UFC's lightweight champion in April 2018 by defeating Al Iaquinta for the vacant belt.
Fight Island will host four UFC events in 14 days, starting with three championship fights at UFC 251 this weekend.
UFC 251: President Dana White reveals mixed martial arts event will be hosted at Abu Dhabi's 'Fight Island'
White had said in April that the UFC was close to securing a private island to stage bouts for international fighters unable to enter the United States due to travel restrictions amid the COVID-19 pandemic.
UFC President Dana White has already said McGregor is next in line for a title shot at the winner of lightweight champion Khabib Nurmagomedov's bout with Justin Gaethje this summer.
UFC 250: Amanda Nunes' power could sell a show light on stars as she defends featherweight title against Felicia Spencer
The overwhelming star attraction of UFC 250 is Nunes (19-4), who turned 32 last week. She last fought in December, and she extended her winning streak to 10 bouts since 2014 with a tough decision over Germaine De Randamie.
The 32-year-old Jones had been eyeing a fight with heavyweight Francis Ngannou, but said the UFC did not want to pay him enough.
UFC 249 could serve as a blueprint for other sports leagues around the country and the world as they start to resume during a global pandemic.
Coronavirus Outbreak: MMA fighters could lose purse, bonuses if found to be criticising UFC 249's health measures
UFC fighters taking part at the UFC 249 event in Florida could lose their purses and bonuses if they publicly criticise the fight promotion’s health and safety precautions for COVID-19, according to an event participation agreement seen by Reuters.
UFC 249 was different — two fighters adjusted their approaches because of what they heard announcers say — and a welcome reprieve for a sports-craved country that went nearly eight weeks with few live events
UFC 249 served as the first major sporting event to take place since the global pandemic shut down much of the country nearly eight weeks ago. It was originally scheduled for 18 April in New York, but was postponed in hopes of helping slow the spread of COVID-19.
'This is going to bring a sense of normalcy': Tony Ferguson, Justin Gaethje headline closed doors UFC 249
UFC 249 will serve as the first major sporting event to take place since the coronavirus pandemic shut down much of the country nearly two months ago.
When the UFC leads North America's major sports back into action Saturday night with a pay-per-view show in Florida, Tony Ferguson and Justin Gaethje know they can't do anything tentatively.
The UFC is aiming to stage a fight card at an undisclosed location on 9 May featuring at least two title bouts, the promotion’s president Dana White has told its broadcast partner ESPN.
UFC 249 was cancelled on Thursday after ESPN and parent company Disney stopped UFC President Dana White’s plan to keep fighting amid the coronavirus pandemic.
Lightweight champion Khabib Nurmagomedov refuses to fight at UFC 249, says he won't break quarantine
UFC didn't immediately comment on Nurmagomedov's decision, which had been expected for several days since the MMA world learned Nurmagomedov was in Dagestan instead of California, where he typically finishes his training for his fights.
Coronavirus pandemic: UFC finally postpones next three scheduled events, confirms president Dana White
The UFC has postponed its next three scheduled events through 11 April, finally giving up on president Dana White's plan to keep fighting amid the coronavirus pandemic.
Coronavirus pandemic: UFC to fight on, tournament president Dana White says sports world is 'panicking'
The UFC is determined to fight on amid the coronavirus pandemic. While leagues and organisers across sports cancelled or delayed competition this week, the UFC proceeded with its plans to hold a fan-free event Saturday night in Brasilia, Brazil. Next weekend, the promotion still plans to stage a full fight card with fans inside London's O2 Arena.
UFC 248: Zhang Weili retains strawweight belt in bruising battle against Joanna Jedrzedczyk; Israel Adesanya wins in snooze-fest
After Zhang and Jedrzejczyk put on one of the most viscerally entertaining bouts in recent UFC history, Romero and Adesanya staged a snoozer that had fans booing and chanting obscenities
Trump sat around 15 feet away as UFC fighters delivered vicious kicks and punches to the face and body of their opponents, regularly drawing blood, at Madison Square Garden.