The victory was Leverkusen's first in five league games and puts them second on goal difference, level on 32 points with RB Leipzig, who host Union Berlin on Wednesday.
For the second consecutive Saturday, Leipzig, who lost 3-1 last weekend at home to Borussia Dortmund, missed out on first place.
What will you think of when you think of 2020? How will you remember sport in a year defined by the pandemic? Here are 20 moments — captured in images and videos — that encapsulate sport in a year like no other:
Bundesliga: Robert Lewandowski's brace takes Bayern Munich to top of table; Marcus Thuram sent off after spitting on opponent's face
Lewandowski, who beat Cristiano Ronaldo and Lionel Messi to the individual award on Thursday, scored in the 93rd minute to put the reigning champions two points clear heading into the winter break.
Champions League: Real Madrid and Zinedine Zidane brace for crucial tie versus Borussia Moenchengladbach
Should Real Madrid suffer a humiliating group stage exit, ending their remarkable run as the only team to ever avoid elimination at this phase, coach Zinedine Zidane's future will be at risk.
UEFA Champions League reaches a crucial final matchday in the group stage with fates of Real Madrid, Inter Milan, Atletico Madrid and Manchester United still unclear.
As per measures announced on Wednesday, all professional sport, including the Bundesliga, must be played behind closed doors until at least the end of November.
Dortmund had three times as many shots on goal and dominated with 80 percent possession, which left their Swiss coach Lucian Favre to admit, "we are very disappointed, it's hard to accept this defeat".
Bundesliga: Erling Haaland double inspires Borussia Dortmund to win over Monchengladbach; Hertha Berlin thump Werder Bremen
Coach Lucien Favre banked on youth by starting two 17-year-olds in Reyna and England Under-21 midfielder Jude Bellingham, who made his league debut, with Sancho and Haaland, both 20, leading Dortmund's attack.
Bundesliga: RB Leipzig reclaims third place after win at Cologne, in line to seal Champions League spot
Leipzig are now third on 58 points, two behind second-placed Borussia Dortmund and nine off leaders Bayern Munich
The DFB said it was reviewing Sancho and Hakimi’s case as well as Schalke’s Weston McKennie, who wore an armband with the slogan “Justice for George”.
Eintracht Frankfurt are struggling to deal with playing in front of empty stands after action in the Bundesliga resumed following a two-month break caused by the COVID-19 pandemic.
Bundesliga talking points: From Bayern Munich's eight-game winning run to Kai Havertz's goal-scoring form
Quick, smart and highly-skilled, Havertz scored twice for the second consecutive game on Sunday as top European clubs are closing in.
Bundesliga: Raphael Guerreiro, Achraf Hakimi score as Dortmund beat Wolfsburg; Kai Havertz bags brace in Bayer win
The result lifted Dortmund to 57 points, one behind Bayern, who are in action against Eintracht Frankfurt later on Saturday. The Bundesliga resumed last week with no fans, after more than two months of suspension due to the COVID-19 pandemic.
Bundesliga returns with fist-bump celebrations and masks as Borussia Dortmund slam four past Schalke
Borussia Dortmund provided much-needed fireworks with a 4-0 demolition of bitter rivals Schalke after Bundesliga restarted in front of empty stands after a suspension of over two months
Bundesliga: Trip for toiletries costs Augsburg coach Heiko Herrlich debut game for breaking quarantine rules
The game against Wolfsburg was to be Herrlich's first game in charge of 14th-place Augsburg. He was appointed in March but had yet to oversee a game because the league was suspended amid the coronavirus pandemic.
These fanless matches, called ‘ghost games’ in Germany, are virtually unknown in the Bundesliga
Bundesliga: All eyes on Germany as football gets going once again with Bayern Munich chasing eighth straight title
Players have been told not to spit, celebrate in groups, or touch hands with team mates, while some Bundesliga clubs will use music and cardboard cutouts of fans to enhance the atmosphere at matches.
Coronavirus Outbreak: Football looks to liven up empty stadiums with cardboard fans, piped applause from app
For many, the real problem of football's “ghost matches” is the lack of noise and eerie atmosphere with the shouts of players and coaching staff echoing around deserted arenas.
What if Europe's top five leagues ended as things stand in the middle of a pandemic enforced standstill?
European leagues are looking to find a solution to the 2019-20 season which has been affected by the coronavirus pandemic. What if champions and relegation was announced based on current positions?