Queen's Club: Andy Murray stunned by Jordan Thompson, Stan Wawrinka and Milos Raonic also crash out
Thompson has never won a Tour title, while Andy Murray has 45, including three Grand Slams, to his credit.
London: Andy Murray suffered one of the most embarrassing defeats of his career as the World No 1 slumped to a stunning Queen's Club first-round defeat by Australia's Jordan Thompson on Tuesday.
Murray was hoping to warm up for his Wimbledon title defence by winning the Queen's title for a sixth time, but instead he succumbed to an astonishing 7-6 (7/4), 6-2 exit against the World No 90.
The 30-year-old's loss was all the more remarkable because Thompson was only called up to face Murray at the last minute.
Murray was scheduled to face Aljaz Bedene, but he withdrew with a wrist injury just hours before Tuesday's match, leaving Thompson, who was at the west London venue as an alternate after losing in the qualifying rounds, to scramble to get ready for his unexpected date with destiny.
With the Queen's champion well below his best, 23-year-old Thompson seized his opportunity in memorable fashion and handed Murray his earliest exit from the tournament since 2012.
"It's a big blow for sure. It's not ideal obviously," said Murray, who has failed to get past the second round in three of his last four tournaments.
"He was better than me. I didn't create loads of chances and didn't return particularly well."
"If I play like that, I certainly won't win Wimbledon."
The shock loss ended Murray's 14-match winning streak on grass and his 10-match unbeaten run at Queen's.
After reaching the French Open semi-finals to raise hopes that he was finally back on track following a poor first half of the season, Murray will head to Wimbledon, which starts on 3 July, with fresh doubts about the state of his game.
"Andy's the world number one. I've looked up to him. That's definitely the biggest win of my career," Thompson said.
"I was sitting around hoping to get a match. I got in the draw and I'm so lucky to be here."
Murray's downfall left Queen's without the top three seeds as World No 3 Stan Wawrinka and World No 6 Milos Raonic also crashed out.
Wawrinka was beaten 7-6 (7/4) 7-5 by Spain's Feliciano Lopez in the Swiss star's first match since being thrashed by Rafael Nadal in the French Open final.
"I'm really sad to have lost. I would have liked more matches here," Wawrinka said.
"There's still a lot of work to do physically and on my game, to be in a better place on grass."
Raonic finished as Queen's and Wimbledon runner-up last year, but the Canadian's hopes of another strong showing on grass were wrecked by Australian wildcard Thanasi Kokkinakis's 7-6 (7/5), 7-6 (10/8) triumph.
"I was just a little too passive. I was letting him dictate too much," Raonic said.
"Obviously the disappointment is high right now."
So far this year, Murray has been mired in a major slump by his sky-high standards after battling shingles, an elbow injury and the flu.
Even so, no one saw this meltdown coming.
Thompson has never won a Tour title, while Murray has 45, including three Grand Slams, to his credit.
But, while Thompson might not have Murray's glittering trophy cabinet, the 23-year-old was already up to speed on grass after reaching the final of the Surbiton Challenger last week.
And in his first match since losing to Wawrinka on the Paris clay, Murray looked all at sea.
Thompson was showing impressive serve and volley prowess and, with Murray lacking focus and fluency, the Australian took advantage to steal the first set tie-break.
When Murray squandered three break points at the start of the second set, Thompson's confidence rose even further.
He out-witted the Wimbledon champion in a long rally to break in the fifth game, then landed the knockout blow with another break before finishing off the bewildered Murray.
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World number eight Berrettini picked up the injury in London where he became the first Italian to reach a Wimbledon singles final, losing in four sets to Novak Djokovic.
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