FIFA World Cup 2018: Portugal finish second in Group B after conceding controversial injury-time penalty against Iran
Ricardo Quaresma curled in a trademark trivela goal but Karim Ansarifard's late penalty dropped Portugal to second in Group B behind neighbours Spain.
Saransk: Cristiano Ronaldo missed a penalty before Portugal conceded an injury-time spot-kick in a 1-1 draw with Iran at the World Cup on Monday as the European champions set up a last-16 clash with Uruguay.
Ricardo Quaresma curled in a trademark trivela goal on the stroke of half-time at the Mordovia Arena, but Karim Ansarifard's late penalty dropped Portugal to second in Group B behind neighbours Spain.
Ronaldo won a second-half spot-kick after a video review but saw his effort saved, with the Real Madrid star unable to add to his four-goal tally at the tournament.
Portugal will face Uruguay in Sochi on 30 July for a place in the quarter-finals after ending Iran's hopes of reaching the knockout phase for the first time.
"I think we did very well, we have achieved our goal and now we have to recover and think about the next match," said Quaresma.
"We know the difficulties we'll face, they're a big team with very good players."
Fernando Santos will hope Joao Moutinho recovers after the Monaco midfielder was restricted to a late substitute appearance in Saransk because of illness, with Quaresma one of three changes to the team that defeated Morocco 1-0.
Ronaldo, scorer of all four Portugal goals in his country's first two games, forced Iran goalkeeper Alireza Beiranvand into an early save after barging his way into the box.
Joao Mario should have put Portugal in front after a defensive mix-up between Saeid Ezatolahi and Beiranvand, but the Inter Milan midfielder blazed over.
Iran's first genuine sight of goal came on 34 minutes when Ezatolahi directed a firm header from a free-kick straight into the grateful hands of Rui Patricio.
Quaresma fired Portugal ahead just before the interval when he exchanged passes with Adrien Silva before bending home in style from the edge of the area with the outside of his right foot.
Ronaldo had the chance to double the lead five minutes into the second half after he was upended by Ezatolahi, with a spot-kick awarded following consultation with the video assistant referee (VAR).
But the Portugal captain was denied by Beiranvand who dived to his left to smother Ronaldo's attempt.
Iran coach Carlos Queiroz remonstrated angrily with the officials as Saman Ghoddos appeared to be impeded by William Carvalho inside the area.
There was no VAR intervention on that occasion, but referee Enrique Caceres trotted over to the pitchside monitor after an altercation between Ronaldo and Morteza Pouraliganji.
Ronaldo caught the Iran defender with a forearm across the face, Pouraliganji falling to the ground in a heap as the Portugal forward ultimately escaped with a yellow card.
Iran earned a stoppage-time penalty, again with the help of VAR, when Sardar Azmoun's header struck the arm of Cedric after the pair contested a deep cross.
Substitute Ansarifard buried his effort into the roof of the net to set up a dramatic finish.
Mehdi Taremi could have snatched a stunning winner after a deflected shot rolled into his path, but he fired into the side netting as Iran fell agonisingly short.
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Ronaldo had been separated from the rest of the Portugal group after testing positive for COVID-19 on Monday. He was said to be asymptomatic and in good health condition.
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As well as Ronaldo, several South Americans including Paulo Dybala, Juan Cuadrado, Danilo and Rodrigo Bentancur also left the Juventus team hotel without awaiting test results this week, according to Italian media reports.
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The Portuguese federation said Ronaldo's result prompted another round of tests for the rest of the national squad. It said everyone else in the team tested negative.