When electronic cigarettes (e-cigarettes) first emerged, they became a popular way for people to quit smoking. But in 2019, a mysterious lung condition emerged that primarily affected young people, particularly those who vaped. This left many questioning the safety of e-cigarettes. The condition was named e-cigarettes or vaping use-associated lung injury — or Evali for short. The average (median) age of people affected by the condition was
24 years
.
Symptoms
included respiratory complaints, such as a cough, shortness of breath and chest pain, as well as stomach problems, fever, chills and weight loss. We now know that Evali is not caused by regulated, commercial nicotine e-cigarettes. Rather, the condition has been
linked to products
sold as THC-containing e-liquids. Because THC (the active ingredient in cannabis) is expensive, some sellers were cutting their products with vitamin E acetate to make the e-liquid look like it contained more THC than it did. Although vitamin E acetate is an ingredient in some foods and skincare products, it’s
harmful when inhaled
. Once the risk from vitamin E acetate was identified, cases of Evali
declined steeply
. But this hasn’t changed many people’s perception of e-cigarettes, with many still concerned about their safety. Misconceptions Despite statements from
Public Health England
and the US
Centers for Disease Control and Prevention
which state that e-cigarettes have the potential to benefit smokers who switch to vaping, concerns about the
dangers of e-cigarettes
, in part because of Evali, are still discouraging people who smoke from switching. In recent surveys,
nearly half
of US and
a third
of British respondents considered nicotine e-cigarettes to be as harmful as cigarettes, if not more harmful. Even after the link to THC-containing products was identified,
most people surveyed
thought that Evali was linked to specific types of nicotine e-cigarettes and not to cannabis or THC-containing products. There are many reasons why misconceptions about the safety of e-cigarettes persist, but undoubtedly it didn’t help that the cause of Evali was
confirmed
just as COVID began dominating news cycles. And, until now, many discussions on e-cigarettes have focused on the risks to young non-smokers. This means the
potential benefits
of e-cigarettes to people who smoke — and those around them — are often ignored.
Research shows
nicotine e-cigarettes can help people quit smoking and may be more effective than nicotine-replacement therapy.
In studies
testing e-cigarettes as a way to quit smoking, there was no evidence that people using e-cigarettes were more likely to experience serious health issues. Also, e-cigarettes are thought to
pose fewer risks to bystanders
— while
secondhand smoke
from cigarettes kills around 1.2 million people a year. It’s also worth noting that e-cigarettes typically only contain nicotine, not tobacco, which is found in cigarettes. Although nicotine is an addictive substance,
tobacco smoke
contains carbon monoxide, tar and toxic chemicals — including benzene, arsenic and formaldehyde.
These substances
are known to cause cancer and other heart and lung diseases. The harm from cigarettes largely comes from
burning tobacco
– not from the nicotine. E-cigarettes deliver nicotine without burning anything. Valid concerns E-cigarettes haven’t been around for long, so they’re very unlikely to be completely harmless, and there is still uncertainty about their longer-term effects. The liquid and vapour used in e-cigarettes contain some potentially harmful chemicals also found in cigarette smoke, but at
lower levels
. In addition, there are concerns about the effect of nicotine on adolescent brain development. Although, as a
recent paper
pointed out, studies showing that nicotine causes changes in the brain have only been conducted on animals. The authors argue it is still unclear whether the same effect will be seen in humans. There are also worries that e-cigarettes could be another pathway to nicotine addiction – especially if people who would never have started smoking begin vaping. In reality, because e-cigarettes are relatively new, uncertainty about their longer-term effects will undoubtedly persist for some time. What we do know is that smoking
disproportionately harms
people from disadvantaged groups, including those from lower-income groups and people with mental health conditions. Not only is smoking linked to many harmful diseases, it’s also
killed more people than COVID
– around
720,000
in the US since March 2020. The evidence we have so far shows that e-cigarettes can be an effective way to help people successfully quit smoking – and are likely to have far fewer health risks than cigarettes. When we communicate about the risks of e-cigarettes, we need to be clear about which e-cigarettes, who might be at risk, and who might benefit. The people who stand to benefit the most from vaping – namely people who smoke – have a right to be receiving accurate, evidence-based information, too. Jamie Hartmann-Boyce is a senior research fellow, departmental lecturer, and director of evidence-based healthcare DPhil programme at the Centre for Evidence-Based Medicine, University of Oxford. This article is republished from
The Conversation
under a Creative Commons license.