Roche buys U.S. biotech Jecure in race for liver disease drugs

ZURICH (Reuters) - Swiss drugmaker Roche is buying U.S.-based Jecure Therapeutics, joining Pfizer , Gilead Sciences and Novartis in pursuit of new drugs to treat fatty liver disease. Roche did not say how much it was paying for Jecure, which gives it a preclinical portfolio of so-called NLRP3 inhibitors being developed for fighting inflammatory diseases like non-alcoholic steatohepatitis (NASH) and liver fibrosis as well as gout, inflammatory bowel disease and cardiovascular diseases. Novartis and Pfizer last month teamed up to develop treatments for NASH, which many drug companies believe will become a hugely lucrative market, as it is tied to the obesity and diabetes epidemics

Reuters November 28, 2018 01:05:14 IST
Roche buys U.S. biotech Jecure in race for liver disease drugs

Roche buys US biotech Jecure in race for liver disease drugs

ZURICH (Reuters) - Swiss drugmaker Roche is buying U.S.-based Jecure Therapeutics, joining Pfizer , Gilead Sciences and Novartis in pursuit of new drugs to treat fatty liver disease.

Roche did not say how much it was paying for Jecure, which gives it a preclinical portfolio of so-called NLRP3 inhibitors being developed for fighting inflammatory diseases like non-alcoholic steatohepatitis (NASH) and liver fibrosis as well as gout, inflammatory bowel disease and cardiovascular diseases.

Novartis and Pfizer last month teamed up to develop treatments for NASH, which many drug companies believe will become a hugely lucrative market, as it is tied to the obesity and diabetes epidemics. Unchecked, NASH can lead to advanced cirrhosis and liver failure.

"We're excited to combine Jecure's portfolio with our discovery and development capabilities, as well as our expertise in NLRP3 biology, to potentially help people with inflammatory diseases," James Sabry, Roche's head of partnering, said in a statement on Tuesday.

NASH, so far with no approved treatments, is poised to become the leading cause of liver transplants by 2020. [https://reut.rs/2HojtnT]

Jecure Therapeutics is focused on novel therapeutics for the treatment of NASH and liver fibrosis and was founded by Dr. Ariel Feldstein, who heads gastroenterology at the University of California San Diego School of Medicine.

(Reporting by John Miller; Editing by Alexander Smith)

This story has not been edited by Firstpost staff and is generated by auto-feed.

Updated Date:

TAGS:

also read

France, Germany to agree to NATO role against Islamic State - sources
| Reuters
World

France, Germany to agree to NATO role against Islamic State - sources | Reuters

By Robin Emmott and John Irish | BRUSSELS/PARIS BRUSSELS/PARIS France and Germany will agree to a U.S. plan for NATO to take a bigger role in the fight against Islamic militants at a meeting with President Donald Trump on Thursday, but insist the move is purely symbolic, four senior European diplomats said.The decision to allow the North Atlantic Treaty Organization to join the coalition against Islamic State in Syria and Iraq follows weeks of pressure on the two allies, who are wary of NATO confronting Russia in Syria and of alienating Arab countries who see NATO as pushing a pro-Western agenda."NATO as an institution will join the coalition," said one senior diplomat involved in the discussions. "The question is whether this just a symbolic gesture to the United States

China's Xi says navy should become world class
| Reuters
World

China's Xi says navy should become world class | Reuters

BEIJING Chinese President Xi Jinping on Wednesday called for greater efforts to make the country's navy a world class one, strong in operations on, below and above the surface, as it steps up its ability to project power far from its shores.China's navy has taken an increasingly prominent role in recent months, with a rising star admiral taking command, its first aircraft carrier sailing around self-ruled Taiwan and a new aircraft carrier launched last month.With President Donald Trump promising a US shipbuilding spree and unnerving Beijing with his unpredictable approach on hot button issues including Taiwan and the South and East China Seas, China is pushing to narrow the gap with the U.S. Navy.Inspecting navy headquarters, Xi said the navy should "aim for the top ranks in the world", the Defence Ministry said in a statement about his visit."Building a strong and modern navy is an important mark of a top ranking global military," the ministry paraphrased Xi as saying.