In this photo provided by Quest Diagnostics and the American Cancer Society, Denver Nuggets basketball coach George Karl talks to the media during a news conference at Quest Diagnostics announcing a new cancer study with the American Cancer Society, Tuesday, Nov. 8, 2011, in Denver. Karl is encouraging Denver residents to sign up for a study that aims to follow 300,000 adults over 20 years to help determine what lifestyle, environmental and genetic factors influence cancer risk.