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Nobel discoveries on DNA repair now fuelling cancer drug research | Reuters

Oct 08, 2015    

CHICAGO Cancer researchers are just beginning to understand the ramifications of the fundamental discoveries behind the 2015 Nobel Prizes in Chemistry, which were awarded on Wednesday to three scientists for explaining how cells repair mistakes in DNA that occur when cells divide.When deoxyribonucleic acid (DNA) repair mechanisms fail, they predispose people to cancer. That is especially true of individuals with mismatch repair defects, a mechanism discovered by Paul Modrich of Duke University and the Howard Hughes Medical Institute.Modrich, Tomas Lindahl and Aziz Sancar won the prize for &quo...

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