London: Manchester City suffered their first defeat under manager Pep Guardiola as Tottenham Hotspur underlined their Premier League title credentials with a 2-0 win at White Hart Lane on Sunday.
Meanwhile, reigning champions Leicester City were held to a goalless draw by Southampton while Manchester United endured a frustrating 1-1 draw at home to Stoke City. Arsenal left it late to secure a 1-0 win at Burnley and move within two points of Manchester City at the top of the table.
An Aleksandar Kolarov own goal and a Dele Alli strike gave Spurs victory and they could even afford for Erik Lamela to squander a second-half penalty.
The result lifted Spurs to second, a point below City.
It was Guardiola's first defeat in 12 games as City manager and followed a mid-week 3-3 draw at Celtic in the Champions League that ended his side's perfect start to the season.
"They (Tottenham) were better," said Guardiola. "We were not in the right positions, so congratulations to them.
"I am not here for the talk around me; I am here to do my job. It is October. You cannot imagine my team is already done."
The result gave Spurs boss Mauricio Pochettino just his second league win over Guardiola in 10 matches, and the first since Espanyol beat Barcelona in the coaches' first such encounter in February 2009.
"It was a great, great victory for us against this opposition. I am very happy," Pochettino said.
At Old Trafford, it looked as if substitute Anthony Martial's 69th-minute goal would give United victory over a Stoke side who started the day bottom of the table.
But a mistake by United goalkeeper David de Gea led to Joe Allen's equaliser eight minutes from time, the point gained seeing Stoke leapfrog Sunderland.
United wasted numerous chances, with world-record signing Paul Pogba and Zlatan Ibrahimovic among the offenders as Stoke goalkeeper Lee Grant, on loan from Derby County, made several fine saves.
"This is the best performance all season and could have been one of these fat results in the Premier League, it could have been 5-0 or 6-0," United manager Jose Mourinho told BT Sport.
"We had big chances, with amazing saves and big misses."
Stoke manager Mark Hughes said: "I'm really pleased with the performance.
"We had a game plan and we executed it to the letter."
Turning to Grant's display, former United striker Hughes said: "He's a good keeper, a great character and we are pleased he is with us."
Elsewhere, strikers Jamie Vardy of Leicester and Charlie Austin of Southampton both missed chances in a drab goalless stalemate, with England caretaker manager Gareth Southgate among the crowd at the King Power Stadium before naming his first squad for the forthcoming World Cup qualifiers against Malta and Slovenia.
The draw left Leicester marooned in mid-table, with hopes of a successful title defence fading fast.
Leicester, however, defeated Porto in midweek to secure a second successive victory in their maiden Champions League campaign and manager Claudio Ranieri was not downbeat over Sunday's result.
"Everything is a new experience," he said. "I'm very relieved because Southampton deserved to win."
Arsenal leave it late
Arsenal scored with virtually the last touch of the game to beat Burnley 1-0 and extend its winning run in the Premier League to five games on Sunday.
After a short corner in the second minute of injury time, Theo Walcott flicked on a cross and Alex Oxlade-Chamberlain appeared to turn the ball in at the far post — via the unintentional hand of teammate Laurent Koscielny just in front of him.
It was a memorable way for Arsene Wenger to mark his 20th anniversary as Arsenal manager. His team is in third place, two points behind leader Manchester City.
Despite being on the back foot for most of the game and defending deeply, Burnley almost took the lead when Michael Keane headed a corner against the crossbar in the 75th minute.
Alexis Sanchez shot wide with Arsenal's best two chances before the visitors' scrambled winner.