Inter Milan showed a lot of composure to secure a morale-boosting 2-1 win over defending champions Juventus while hosts Fiorentina overcame Roma 1-0 in Serie A football league.
Juventus on Sunday succumbed to their first league reverse of the season, just their second in 32 Serie A outings as goals from Mauro Icardi and Ivan Perisic cancelled out Stephan Lichtsteiner's second-half opener at the San Siro stadium.
In Fiorence's Stadio Artemio Franchi, midfielder Milan Badelj's 82nd minute strike helped the hosts end Roma's 20-game undefeated streak in Serie A as the Serie A weekend culminated with the two big matches.
At the end of the weekend, last season's runners-up Napoli are on the lead with 10 points from four matches as Juventus dropped to the second spot with nine points.
Roma, remained in the third spot with seven points, followed by Lazio, Chievo and Inter -- all with seven points.
Inter's win comes as a big relief to new head coach Frank De Boer who was under pressure after seeing his side suffer loss to league side Chievo and Hapoel Be'er Sheva in the Europa League.
But Inter rose to the occassion in the much-talked fixture, reverred as the Derby d'Italia.
After a cagey and tightly fought first period, the game came to life after the break as Icardi and Perisic struck within 10 minutes of each other, the former equalising moments after Lichtsteiner had smashed home from close range, to swing the 167th in favour of the hosts.
Frank De Boer's side completed the tie with 10 men after Ever Banega was dismissed for two bookable offences but in the end it mattered little as Juventus failed to muster the game's fourth goal in the closing stages.
Meanwhile in Fiorence, it was a tale of two posts for Roma as Badelj fired home via the woodwork -- seconds after Radja Nainggolan had seen his effort bounce clear in similar fashion -- to secure the win for the hosts.
Badelj found the bottom corner from 20 yards in the 82nd minute to win it for his side, who had created few clear-cut chances of note over the 90 minutes.
It was a bitter blow for the visitors to take, having seen Nainggolan hit the post and substitute Stephan El Shaarawy denied at the death.
There was further controversy to the goal -- replay suggested Fiorentina striker Nikola Kalinic had been in an offside position as he jumped out of the way of Badelj's shot on the way to goal -- but referee Nicola Rizzoli saw no issue.
Meanwhile in the Bundesliga, illness to defenders Philipp Lahm, David Alaba, Mats Hummels and forward Thomas Mueller meant Bayern coach Carlo Ancelotti rang the changes for Saturday's 3-1 comeback win against Ingolstadt.
Paraguay striker Dario Lezcano scored after just eight minutes, but goals by Robert Lewandowski, Xabi Alonso and Rafinha preserved Bayern's 100 percent record.
Ancelotti praised his side's character, but Germany captain Manuel Neuer, rock solid in Bayern's goal, was their hero.
He twice denied Ingolstadt's Mathew Leckie from close range, including a superb save just after the break, as the visitors created 13 chances, compared to Bayern's ten.
"Thank god we have Manuel Neuer in goal," said Rafinha.
In other news, fresh from Wednesday's 6-0 Champions League drubbing of Legia Warsaw, Borussia Dortmund ran up another tennis score in their 6-0 hammering at home to Darmstadt.
The 12 goals from 10 different players came after coach Thomas Tuchel left stars Mario Goetze and Pierre-Emerick Aubameyang on the bench against Darmstadt.
"It would be nice if a 6-0 win becomes our standard result," quipped Dortmund's Germany midfielder Julian Weigl.
Their shock 1-0 defeat at newly-promoted RB Leipzig last weekend means Dortmund have six points from a possible nine.
Tuchel warns they face tougher challenges at Wolfsburg on Tuesday and Freiburg at home on Friday before hosting Real Madrid in a plum Champions League group stage tie on September 27.
"We were clear favourites (against Legia and Darmstadt) and will be tested on Tuesday and Friday," said Tuchel.
In the English Premier League Kevin De Bruyne scored one goal and helped make another in last weekend's 2-1 win at Manchester United and was equally influential in the 4-0 victory over Bournemouth
Friday's 2-1 win at Chelsea was another lesson in asphyxiating intensity and breathless endeavour. Dejan Lovren's volley and Jordan Henderson's superb long-range curler put the visitors in control and although Diego Costa reduced the arrears, the margin of victory was misleading -- Liverpool were never in trouble.
In the Spanish La Liga, without the ill Cristiano Ronaldo and injured Gareth Bale, Real Madrid laboured for 45 minutes at Espanyol until James Rodriguez fired home the opener just before the break to pave the way to a 2-0 win.
Leganes tried to make Barcelona's first ever La Liga trip to the Butarque as uncomfortable as possible by relentlessly pressing the champions deep into their own half for the first 15 minutes on Saturday's clash.
The lethal strike force of Lionel Messi, Luis Suarez and Neymar (MSN) were on target in a 5-1 thrashing that showed Barca's ability and willingness to play on the counter-attack on the rare occasions the opposition leaves plenty of space for the MSN to exploit.
(With inputs from agencies)